RBR-7b5ycz U1111-1128-5307 REBEC 26/04/2012 Universidade Federal do Paraná - Curitiba, PR, Brazil Evaluation of dressing for central venous catheter Evaluation of the effectiveness of the chlorhexidine antimicrobial dressing for central venous catheter : ClorHexidine Gluconate-Central Venous Catheter 17/10/2011 actual 84 recruiting http://www.ensaiosclinicos.gov.br/rg/RBR-7b5ycz/ Preventive, parallel, 2-arms, open, randomized controlled clinical trial. N/A Catheter-related bloodstream infection 84 patients using the first central venous catheter within 24 hours of insertion of the short-term catheter will be randomized to form two groups. Study group: 42 patients receive curative antimicrobial chlorhexidine. Control group: 42 patients receive Sterile gauze. The patient will be monitored and evaluated daily by the research team for collection of signs and symptoms, medications used, the dressing conditions and socio-demographic data. The dressing is changed every seven days in the study group and control group in every 48 hours, or when loose, moist dirt or signs that compromise its integrity. Patients will be followed until catheter removal or even puncture a second central catheter.

public Edivane Pedrolo

Av. Prof. Lothario Meissner, 632, sala 12, 3 andar

Curitiba Brazil 80210170 41 99255226 edivanepedrolo@gmail.com Universidade Federal do Paraná scientific Edivane Pedrolo

Av. Prof. Lothario Meissner, 632, sala 12, 3 andar

Curitiba Brazil 80210170 41 99255226 edivanepedrolo@gmail.com Universidade Federal do Paraná Brazil Over 18 years; Hospitalization in the Intensive Care Unit (ICU) or Semi Intensive (CTSI) Adult; In the first use of central venous catheter (CVC) for short stay less than 24 hours; Signing the consent form; No known sensitivity to materials of the dressings. 18Y 100Y - Refusal by the patient or explained by the family to participate in the research; By shaving blade at the site of catheter insertion prior to puncture; Sweating or bleeding from the orifice of the catheter; Temperature above 38 ° C during puncture of the catheter. C01 C01.539.195 other E07.132 Reduction of bloodstream infection related to the catheter by the use of antimicrobial chlorhexidine dressings as measured by infection rate per thousand catheter days in both groups. Increased rate of fixation of the skin healing evaluated by displacement of borders with or without compromising the integrity of the dressing. Will be considered adequate fixation when the dressing remains intact. Reduction of local reaction to the healing assessed by the absence of itching, redness, scaling and maceration in the region of contact with skin healing. 3M do Brasil - Sumaré, SP, Brazil CAAE 0067.0.091.208-11 Comitê de Ética em Pesquisa do Setor de Ciências da Saúde da Universidade Federal do Paraná CEP/SD 1145.070.11.06 Comitê de Ética em Pesquisa do Setor de Ciências da Saúde da Universidade Federal do Paraná 3M do Brasil - Sumaré, SP, Brazil